Knowledge Base

Have you ever wondered how superresolution microscopy works? What’s the difference between STED, STORM, and MINFLUX? What is “resolution” and what is a “PSF”? What is so special about the STEDYCON? Read on to find out.

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Everything about microscopes, dyes and superresolution

So, you thought you knew what resolution is but were surprised to find out that light caps the detail of microscope images. There are workarounds, however, that bring increasingly fine detail into focus. Those workarounds push the boundaries of what we can resolve by manipulating where and when we detect signals from a specimen and thus, expand the levers we have to shrink the distance between two points.