Since the 1990s, confocal microscopes have been a staple in labs visualizing biological or material specimens. The development of STED microscopy prompted the question: how does the established confocal microscope compare to the (now not so) “new kid on the block”? Details >
Knowledge Base
Have you ever wondered how superresolution microscopy works? What’s the difference between STED, STORM, and MINFLUX? What is “resolution” and what is a “PSF”? What is so special about the STEDYCON? Read on to find out.
If you have any suggestions, questions or ideas for our knowledge base, we would be very happy to hear from you.
ContactEverything about microscopes, dyes, and superresolution
All
#2photon
#abberationcorrection
#aberrationcorrection
#adaptiveillumination
#adaptiveoptics
#antibody
#arraydetection
#basicprinciples
#biology
#comparison
#confocal
#deformablemirror
#diffractionlimit
#donut
#ExM
#fluorescence
#fourier
#immunofluorescence
#labeling
#laser
#lightmicroscopy
#livingcells
#MATRIX
#MINFLUX
#modules
#nanobody
#nanometer
#optics
#PAINT
#PALM
#resolution
#selflabelingproteins
#SIM
#SMLM
#STED
#STEDYCON
#STORM
#superresolution
#TEM
#tracking
#virology
#widefield
Confocal microscopy offers superior optical sectioning. But what is that exactly? And what about other ways to get rid of the background, such as array-based detectors like the MATRIX? Details >
Deep and clear: where confocal beats out wide-field microscopy
![Confocal vs Wide-field](https://abberior.rocks/wp-content/uploads/00272_Confocal_vs_Widefield-1200x320.jpg)
Confocal microscopes were designed to get rid of background signal. How do they work? And when do you know it’s time to use one? The answer is in the pinhole. Details >