abberior dyes & labels
Angewandte Chemie International Edition
Photochromic rhodamines provide nanoscopy with optical sectioning
Fölling, J., Belov, V., Kunetsky, R., Medda, R., Schönle, A., Egner, A., ... & Hell, S. E.
photochromism, photoswitchable compounds
Exciting developments: Switching individual photochromic and fluorescent rhodamine amides enables 3D far-field optical microscopy with nanoscale resolution, excellent signal-to-noise ratio, and fast acquisition times. The rhodamine amides can be switched on using two photons, which enables 3D detailed imaging of thick and densely stained samples (such as 5-μm silica beads (see image) and living cells) to be constructed.