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Science beyond Barriers

abberior dyes & labels

2015
Chemical Communications

A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry

Authors:

Kabatas, S., Vreja, I. C., Saka, S. K., Höschen, C., Kröhnert, K., Opazo, F., ... & Diederichsen, U.

Abstract:

Imaging techniques should differentiate between specific signals, from the biomolecules of interest, and non-specific signals, from the background. We present a probe containing 15N and 14N isotopes in approximately equal proportion, for secondary ion mass spectrometry imaging. This probe designed for a precise biomolecule analysis is insensitive to background signals.

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