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Journal of Traditional Chinese Medical Sciences |
Wang, M., et al. |
Mechanism of action of Xipayimaizibizi oral liquid on outlet obstruction-induced overactive bladder: An integrated study |
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| 2024 |
Advanced Science |
Xiao, P.-T., et al. |
Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice |
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| 2024 |
Science Advances |
Ahola, S., et al. |
Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy |
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| 2024 |
PNAS |
Weninger, G., et al. |
Structural insights into the regulation of RyR1 by S100A1 |
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| 2024 |
Nature |
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Molecular definition of the endogenous Toll-like receptor signalling pathways |
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| 2024 |
MDPI |
López-Martínez, M., et al. |
Integrated miRNA–mRNA Analysis Reveals Critical miRNAs and Targets in Diet-Induced Obesity-Related Glomerulopathy |
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| 2024 |
Photonics |
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In Situ Structural Characterization of Cardiomyocyte Microenvironment by Multimodal STED Microscopy |
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| 2024 |
Nature |
Schwenzer, N., et al. |
CaV1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy |
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| 2024 |
Aging Cell |
Cavinato, M., et al. |
Elimination of damaged mitochondria during UVB-induced senescence is orchestrated by NIX-dependent mitophagy |
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| 2024 |
Nature Communications |
Parlakgül, G., et al. |
Spatial mapping of hepatic ER and mitochondria architecture reveals zonated remodeling in fasting and obesity |
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| 2024 |
British Journal of Pharmacology |
Liepinsh, E., et al. |
Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver |
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| 2024 |
Materials Today Bio |
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From static to dynamic: The influence of mechanotransduction on skin equivalents analyzed by bioimaging and RNAseq |
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| 2024 |
Bioactive Materials |
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Extracellular matrix stiffness as an energy metabolism regulator drives osteogenic differentiation in mesenchymal stem cells |
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| 2024 |
Nature |
Schömig, T., et al. |
The podocytes’ inflammatory responses in experimental GN are independent of canonical MYD88-dependent toll-like receptor signaling |
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| 2023 |
J Neuroinflammation |
Pfaller, A.M., et al. |
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice |
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| 2024 |
Nature Communications |
Ye, Z., et al. |
Structural heterogeneity of the ion and lipid channel TMEM16F |
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| 2023 |
Journal of Experimenta Medicine |
Lund, H., et al. |
CD163+ macrophages monitor enhanced permeability at the blood–dorsal root ganglion barrier |
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| 2023 |
Science Advances |
Barone, I., et al. |
Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity |
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| 2023 |
PLOS genetics |
Roca-Umbert, A., et al. |
Human genetic adaptation related to cellular zinc homeostasis |
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| 2023 |
PLOS one |
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Characterization of Fibrodysplasia Ossificans Progessiva relevant Acvr1/Acvr2 Activin receptors in medaka (Oryzias latipes) |
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| 2023 |
The Journal of Clinical Investigation |
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Patient-derived Enteroids provide a Platform for the Development of Therapeutic Approaches in Microvillus Inclusion Disease |
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| 2023 |
Cell Death & Disease |
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Targeted deletion of von-Hippel-Lindau in the proximal tubule conditions the kidney against early diabetic kidney disease |
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| 2023 |
bioRxiv |
Tamborrini, D., et al. |
In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament |
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| 2023 |
JCI insight |
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EGFR inhibition leads to enhanced desmosome assembly and cardiomyocyte cohesion via ROCK activation |
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Life |
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Increased Mitochondrial Calcium Fluxes in Hypertrophic Right Ventricular Cardiomyocytes from a Rat Model of Pulmonary Artery Hypertension |
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| 2023 |
The American Journal of Pathology |
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TRPV1 dysfunction impairs gastric nitrergic neuromuscular relaxation in high fat diet induced diabetic gastroparesis mice |
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| 2023 |
bioRxiv |
Smits, M.A.J., et al. |
Human ovarian ageing is characterized by oxidative damage and mitochondrial dysfunction |
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| 2023 |
Journal of Cell Biology |
Bebelman, M. P., et al. |
Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure |
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| 2023 |
bioRxiv |
Kalashyan, M., et al. |
Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids |
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Chemosensors |
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New ICT-based Ratiometric Two-Photon Near Infrared Probe for Imaging Tyrosinase in Living Cells, Tissues and Whole Organisms |
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Nature Communications |
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Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus |
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Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M) |
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Cellular and Molecular Life Sciences |
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Cytoskeletal anchorage of diferent Dsg3 pools revealed by combination of hybrid STED/SMFS‑AFM |
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Megalin Orchestrates FcRn Endocytosis and Trafficking |
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European Journal of Medicinal Chemistry |
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New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action |
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Molecular Psychiatry |
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Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans |
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ScienceSignaling |
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VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney |
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Mitochondrion |
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Tissue imaging reveals disruption of epithelial mitochondrial networks and loss of mitochondria-associated cytochrome-C in inflamed human and murine colon |
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Colloids and Surfaces B: Biointerfaces |
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Aggregation mechanism and branched 3D morphologies of pathological human light chain proteins under reducing conditions |
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Scientific Reports |
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Immune mobilising T cell receptors redirect polyclonal CD8+ T cells in chronic HIV infection to form immunological synapses |
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Nature Communications |
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Multiciliated cells use filopodia to probe tissue mechanics during epithelial integration in vivo |
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| 2022 |
Science Advances |
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Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner |
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| 2022 |
Proceedings of the National Academy of Sciences |
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Polycomb group (PcG) proteins prevent the assembly of abnormal synaptonemal complex structures during meiosis |
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BMC biology |
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Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes |
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Nature Communications |
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Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation |
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Journal of nanobiotechnology |
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Fast, streamlined fluorescence nanoscopy resolves rearrangements of SNARE and cargo proteins in platelets co-incubated with cancer cells |
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Journal of Cell Biology |
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Cholesterol promotes clustering of PI (4, 5) P2 driving unconventional secretion of FGF2 |
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Nature communications |
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Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes |
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Kidney International |
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Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier |
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Analytical Biochemistry |
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Fluorescence-encoded Poly (methyl metharcylate) nanoparticles for a lateral flow assay detecting IgM autoantibodies in rheumatoid arthritis |
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Analytical and Bioanalytical Chemistry |
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Superresolving the kidney—a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier |
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Advanced Materials |
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Prediction of chronic inflammation for inhaled particles: The impact of material cycling and quarantining in the lung epithelium |
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Gastroenterology |
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Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface |
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Nature communications |
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T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration |
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Nature communications |
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Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice |
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Nature communications |
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Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics |
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Proceedings of the National Academy of Sciences |
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Resolving titin’s lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes |
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The FASEB Journal |
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Localization of group II and III metabotropic glutamate receptors at pre‐and postsynaptic sites of inner hair cell ribbon synapses |
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Science immunology |
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T cell receptor–triggered nuclear actin network formation drives CD4+ T cell effector functions |
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Nature communications |
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Quantitative optical nanophysiology of Ca 2+ signaling at inner hair cell active zones |
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Scientific reports |
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Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase |
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Frontiers in cellular neuroscience |
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Rab interacting molecules 2 and 3 directly interact with the pore-forming CaV1. 3 Ca2+ channel subunit and promote its membrane expression |
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Scientific reports |
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Hyperosmolarity impedes the cross-priming competence of dendritic cells in a TRIF-dependent manner |
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Biophysical journal |
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Reorganization of lipid diffusion by myelin basic protein as revealed by STED nanoscopy |
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The EMBO journal |
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Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis |
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Journal of Experimental Medicine |
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Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis |
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Tomographic STED microscopy to study bone resorption |
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Journal of molecular and cellular cardiology |
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Superresolution microscopy in heart—Cardiac nanoscopy |
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Development |
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Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear |
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Cellular and Molecular Life Sciences |
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Pharmacological chaperone-rescued cystic fibrosis CFTR-F508del mutant overcomes |
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